Biochemical and Structural Characterization of the Subclass B1 Metallo-β-Lactamase VIM-4

The metallo-β-lactamase VIM-4, mainly found in Pseudomonas aeruginosa or Acinetobacter baumannii, was produced in Escherichia coli and characterized by biochemical and X-ray techniques. A detailed kinetic study performed in the presence of Zn(2+) at concentrations ranging from 0.4 to 100 μM showed t...

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Detalhes bibliográficos
Main Authors: Lassaux, Patricia, Traoré, Daouda A. K., Loisel, Elodie, Favier, Adrien, Docquier, Jean-Denis, Sohier, Jean Sébastien, Laurent, Clémentine, Bebrone, Carine, Frère, Jean-Marie, Ferrer, Jean-Luc, Galleni, Moreno
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2011
Assuntos:
Mechanisms of Resistance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3067066/
https://ncbi.nlm.nih.gov/pubmed/21149620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01486-09
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