Clofazimine Analogs with Efficacy against Experimental Tuberculosis and Reduced Potential for Accumulation

The global tuberculosis crisis urgently demands new, efficacious, orally available drugs with the potential to shorten and simplify the long and complex treatments for drug-sensitive and drug-resistant disease. Clofazimine, a riminophenazine used for many years to treat leprosy, demonstrates efficac...

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Autori principali: Lu, Yu, Zheng, Meiqin, Wang, Bin, Fu, Lei, Zhao, Weijie, Li, Peng, Xu, Jian, Zhu, Hui, Jin, Haixia, Yin, Dali, Huang, Haihong, Upton, Anna M., Ma, Zhenkun
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2011
Soggetti:
Experimental Therapeutics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3195009/
https://ncbi.nlm.nih.gov/pubmed/21844321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00699-11
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