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Plasma and Intracellular Population Pharmacokinetic Analysis of Tenofovir in HIV-1-Infected Patients

The relationships among the dose of tenofovir disoproxil fumarate (TDF), tenofovir (TFV) plasma concentrations, and intracellular TFV diphosphate (TFV-DP) concentrations are poorly understood. Our objective was to characterize TFV and TFV-DP relationships. Data were pooled from two studies in HIV-in...

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Détails bibliographiques
Auteurs principaux: Baheti, Gautam, Kiser, Jennifer J., Havens, Peter L., Fletcher, Courtney V.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3194996/
https://ncbi.nlm.nih.gov/pubmed/21896913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05317-11
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