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Age-related differences in plasma and intracellular tenofovir concentrations in HIV-1 infected children, adolescents and adults

INTRODUCTION: There is limited pediatric information on the complex relationships among the dose of tenofovir disoproxil fumarate (TDF), plasma concentrations of tenofovir (TFV), and intracellular TFV-diphosphate (TFV-DP) concentrations. Our objectives were to describe TFV-DP pharmacokinetics in chi...

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Detalhes bibliográficos
Main Authors: Baheti, Gautam, King, Jennifer R., Acosta, Edward P., Fletcher, Courtney V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3586236/
https://ncbi.nlm.nih.gov/pubmed/23032419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0b013e32835a9a2d
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