Chargement en cours...
An NMR strategy for fragment-based ligand screening utilizing a paramagnetic lanthanide probe
A nuclear magnetic resonance-based ligand screening strategy utilizing a paramagnetic lanthanide probe is presented. By fixing a paramagnetic lanthanide ion to a target protein, a pseudo-contact shift (PCS) and a paramagnetic relaxation enhancement (PRE) can be observed for both the target protein a...
Enregistré dans:
| Auteurs principaux: | , , , , , |
|---|---|
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Springer Netherlands
2011
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3193990/ https://ncbi.nlm.nih.gov/pubmed/21927934 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10858-011-9566-5 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|