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The TRAF-associated protein TANK facilitates cross-talk within the IκB kinase family during Toll-like receptor signaling
Toll-like receptor (TLR) ligands that signal via TIR-domain-containing adapter-inducing IFNβ (TRIF) activate the IκB kinase (IKK)-related kinases, TRAF associated NFκB activator (TANK)-binding kinase-1 (TBK1) and IKKε, which then phosphorylate IRF3 and induce the production of IFNβ. Here we show tha...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3193242/ https://ncbi.nlm.nih.gov/pubmed/21949249 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1114194108 |
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