Exome sequencing identifies a spectrum of mutation frequencies in advanced and lethal prostate cancers

To catalog protein-altering mutations that may drive the development of prostate cancers and their progression to metastatic disease systematically, we performed whole-exome sequencing of 23 prostate cancers derived from 16 different lethal metastatic tumors and three high-grade primary carcinomas....

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Kumar, Akash, White, Thomas A., MacKenzie, Alexandra P., Clegg, Nigel, Lee, Choli, Dumpit, Ruth F., Coleman, Ilsa, Ng, Sarah B., Salipante, Stephen J., Rieder, Mark J., Nickerson, Deborah A., Corey, Eva, Lange, Paul H., Morrissey, Colm, Vessella, Robert L., Nelson, Peter S., Shendure, Jay
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2011
Pynciau:
Biological Sciences
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3193229/
https://ncbi.nlm.nih.gov/pubmed/21949389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1108745108
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg