Exome sequencing identifies a spectrum of mutation frequencies in advanced and lethal prostate cancers

To catalog protein-altering mutations that may drive the development of prostate cancers and their progression to metastatic disease systematically, we performed whole-exome sequencing of 23 prostate cancers derived from 16 different lethal metastatic tumors and three high-grade primary carcinomas....

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Detaylı Bibliyografya
Asıl Yazarlar: Kumar, Akash, White, Thomas A., MacKenzie, Alexandra P., Clegg, Nigel, Lee, Choli, Dumpit, Ruth F., Coleman, Ilsa, Ng, Sarah B., Salipante, Stephen J., Rieder, Mark J., Nickerson, Deborah A., Corey, Eva, Lange, Paul H., Morrissey, Colm, Vessella, Robert L., Nelson, Peter S., Shendure, Jay
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2011
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3193229/
https://ncbi.nlm.nih.gov/pubmed/21949389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1108745108
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