Exome sequencing identifies a spectrum of mutation frequencies in advanced and lethal prostate cancers

To catalog protein-altering mutations that may drive the development of prostate cancers and their progression to metastatic disease systematically, we performed whole-exome sequencing of 23 prostate cancers derived from 16 different lethal metastatic tumors and three high-grade primary carcinomas....

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Detalhes bibliográficos
Main Authors: Kumar, Akash, White, Thomas A., MacKenzie, Alexandra P., Clegg, Nigel, Lee, Choli, Dumpit, Ruth F., Coleman, Ilsa, Ng, Sarah B., Salipante, Stephen J., Rieder, Mark J., Nickerson, Deborah A., Corey, Eva, Lange, Paul H., Morrissey, Colm, Vessella, Robert L., Nelson, Peter S., Shendure, Jay
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3193229/
https://ncbi.nlm.nih.gov/pubmed/21949389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1108745108
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