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Pharmacogenetics and population pharmacokinetics: impact of the design on three tests using the SAEM algorithm

Pharmacogenetics is now widely investigated and health institutions acknowledge its place in clinical pharmacokinetics. Our objective is to assess through a simulation study, the impact of design on the statistical performances of three different tests used for analysis of pharmacogenetic informatio...

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Detalhes bibliográficos
Main Authors: Bertrand, Julie, Comets, Emmanuelle, Laffont, Céline, Chenel, Marylore, Mentré, France
Formato: Artigo
Idioma:Inglês
Publicado em: Springer 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3192406/
https://ncbi.nlm.nih.gov/pubmed/19562469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10928-009-9124-x
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