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Metrics for external model evaluation with an application to the population pharmacokinetics of gliclazide

PURPOSE: The aim of this study is to define and illustrate metrics for the external evaluation of a population model. METHODS: In this paper, several types of metrics are defined: based on observations (standardized prediction error with or without simulation and normalized prediction distribution e...

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Detalhes bibliográficos
Main Authors: Brendel, Karl, Comets, Emmanuelle, Laffont, Céline, Laveille, Christian, Mentré, France
Formato: Artigo
Idioma:Inglês
Publicado em: Kluwer Academic/Plenum Publishers 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2124466/
https://ncbi.nlm.nih.gov/pubmed/16906454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-006-9067-5
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