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Gene Targeting of the Cysteine Peptidase Cathepsin H Impairs Lung Surfactant in Mice
BACKGROUND: The 11 human cysteine cathepsins are proteases mainly located in the endolysosomal compartment of all cells and within the exocytosis pathways of some secretory cell types. Cathepsin H (Ctsh) has amino- and endopeptidase activities. In vitro studies have demonstrated Ctsh involvement in...
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| 主要な著者: | , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Public Library of Science
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3192174/ https://ncbi.nlm.nih.gov/pubmed/22022579 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0026247 |
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