Role of Monoubiquitylation on the Control of IκBα Degradation and NF-κB Activity

The NF-κB pathway is regulated by multiple post-translational modifications including phosphorylation, ubiquitylation and SUMOylation. Many of these modifications act on the natural inhibitor IκBα modulating its capacity to control signal-mediated NF-κB activity. While the canonical pathway involvin...

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Main Authors: Da Silva-Ferrada, Elisa, Torres-Ramos, Mónica, Aillet, Fabienne, Campagna, Michela, Matute, Carlos, Rivas, Carmen, Rodríguez, Manuel S., Lang, Valérie
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2011
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3192046/
https://ncbi.nlm.nih.gov/pubmed/22022389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025397
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