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Role of Monoubiquitylation on the Control of IκBα Degradation and NF-κB Activity
The NF-κB pathway is regulated by multiple post-translational modifications including phosphorylation, ubiquitylation and SUMOylation. Many of these modifications act on the natural inhibitor IκBα modulating its capacity to control signal-mediated NF-κB activity. While the canonical pathway involvin...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3192046/ https://ncbi.nlm.nih.gov/pubmed/22022389 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025397 |
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