Efficacy of Novel Histone Deacetylase Inhibitor, AR42, in a Mouse Model of Human T-lymphotropic Virus Type 1 Adult T cell Lymphoma

Human T-lymphotropic virus type 1 (HTLV-1) causes a variety of forms of adult T-cell leukemia/lymphoma (ATL), a refractory CD4+/CD25+ T-cell malignancy. Novel approaches to treat ATL patients are required due to the resistance of ATL to conventional chemotherapies. Histone deacetylase inhibitors (HD...

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Main Authors: Zimmerman, Bevin, Sargeant, Aaron, Landes, Kristina, Fernandez, Soledad A., Chen, Ching-Shih, Lairmore, Michael D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3191315/
https://ncbi.nlm.nih.gov/pubmed/21802726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.leukres.2011.07.015
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