טוען...
Elimination of Proliferating Cells Unmasks the Shift from Senescence to Quiescence Caused by Rapamycin
BACKGROUND: Depending on cellular context, p53-inducing agents (such as nutlin-3a) cause different outcomes including reversible quiescence and irreversible senescence. Inhibition of mTOR shifts the balance from senescence to quiescence. In cell lines with incomplete responses to p53, this shift may...
שמור ב:
| Main Authors: | , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Public Library of Science
2011
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3191182/ https://ncbi.nlm.nih.gov/pubmed/22022534 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0026126 |
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