Загрузка...
Elimination of Proliferating Cells Unmasks the Shift from Senescence to Quiescence Caused by Rapamycin
BACKGROUND: Depending on cellular context, p53-inducing agents (such as nutlin-3a) cause different outcomes including reversible quiescence and irreversible senescence. Inhibition of mTOR shifts the balance from senescence to quiescence. In cell lines with incomplete responses to p53, this shift may...
Сохранить в:
| Главные авторы: | , , , |
|---|---|
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Public Library of Science
2011
|
| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3191182/ https://ncbi.nlm.nih.gov/pubmed/22022534 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0026126 |
| Метки: |
Добавить метку
Нет меток, Требуется 1-ая метка записи!
|