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Hypoxia suppresses conversion from proliferative arrest to cellular senescence
Unlike reversible quiescence, cellular senescence is characterized by a large flat cell morphology, β-gal staining and irreversible loss of regenerative (i.e., replicative) potential. Conversion from proliferative arrest to irreversible senescence, a process named geroconversion, is driven in part b...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3421205/ https://ncbi.nlm.nih.gov/pubmed/22847439 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1205690109 |
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