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Ca(2+)-binding activity of a COOH-terminal fragment of the Drosophila BK channel involved in Ca(2+)-dependent activation

Mutational and biophysical analysis suggests that an intracellular COOH-terminal domain of the large conductance Ca(2+)-activated K(+) channel (BK channel) contains Ca(2+)-binding site(s) that are allosterically coupled to channel opening. However the structural basis of Ca(2+) binding to BK channel...

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Detalhes bibliográficos
Main Authors: Bian, Shumin, Favre, Isabelle, Moczydlowski, Edward
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC31910/
https://ncbi.nlm.nih.gov/pubmed/11274367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.081072398
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