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Ca(2+)-binding activity of a COOH-terminal fragment of the Drosophila BK channel involved in Ca(2+)-dependent activation
Mutational and biophysical analysis suggests that an intracellular COOH-terminal domain of the large conductance Ca(2+)-activated K(+) channel (BK channel) contains Ca(2+)-binding site(s) that are allosterically coupled to channel opening. However the structural basis of Ca(2+) binding to BK channel...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2001
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC31910/ https://ncbi.nlm.nih.gov/pubmed/11274367 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.081072398 |
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