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Allosteric Model of Maraviroc Binding to CC Chemokine Receptor 5 (CCR5)

Maraviroc is a nonpeptidic small molecule human immunodeficiency virus type 1 (HIV-1) entry inhibitor that has just entered the therapeutic arsenal for the treatment of patients. We recently demonstrated that maraviroc binding to the HIV-1 coreceptor, CC chemokine receptor 5 (CCR5), prevents it from...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Garcia-Perez, Javier, Rueda, Patricia, Alcami, Jose, Rognan, Didier, Arenzana-Seisdedos, Fernando, Lagane, Bernard, Kellenberger, Esther
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2011
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3190905/
https://ncbi.nlm.nih.gov/pubmed/21775441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.279596
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