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Allosteric Model of Maraviroc Binding to CC Chemokine Receptor 5 (CCR5)
Maraviroc is a nonpeptidic small molecule human immunodeficiency virus type 1 (HIV-1) entry inhibitor that has just entered the therapeutic arsenal for the treatment of patients. We recently demonstrated that maraviroc binding to the HIV-1 coreceptor, CC chemokine receptor 5 (CCR5), prevents it from...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3190905/ https://ncbi.nlm.nih.gov/pubmed/21775441 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.279596 |
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