New Insights into the Mechanisms whereby Low Molecular Weight CCR5 Ligands Inhibit HIV-1 Infection

CC chemokine receptor 5 (CCR5) is a G-protein-coupled receptor for the chemokines CCL3, -4, and -5 and a coreceptor for entry of R5-tropic strains of human immunodeficiency virus type 1 (HIV-1) into CD4(+) T-cells. We investigated the mechanisms whereby nonpeptidic, low molecular weight CCR5 ligands...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Garcia-Perez, Javier, Rueda, Patricia, Staropoli, Isabelle, Kellenberger, Esther, Alcami, Jose, Arenzana-Seisdedos, Fernando, Lagane, Bernard
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2011
Pynciau:
Signal Transduction
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3037610/
https://ncbi.nlm.nih.gov/pubmed/21118814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.168955
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