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Dietary Isothiocyanate-induced Apoptosis via Thiol Modification of DNA Topoisomerase IIα

Studies in animal models have indicated that dietary isothiocyanates (ITCs) exhibit cancer preventive activities through carcinogen detoxification-dependent and -independent mechanisms. The carcinogen detoxification-independent mechanism of cancer prevention by ITCs has been attributed at least in p...

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Autori principali: Lin, Ren-Kuo, Zhou, Nai, Lyu, Yi Lisa, Tsai, Yuan-Chin, Lu, Chang-Hsien, Kerrigan, John, Chen, Yu-tsung, Guan, Ziqiang, Hsieh, Tao-Shih, Liu, Leroy F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3190902/
https://ncbi.nlm.nih.gov/pubmed/21828038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.258137
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