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The multiple shark immunoglobulin heavy chain genes rearrange and hypermutate autonomously()
Sharks and skates are representatives of the earliest vertebrates with an immune system based on V(D)J rearrangement. They possess a unique Ig gene organization consisting of 15 to >50 individual IgM loci, each with one VH, two DH, one JH and one set of constant region exons. The present study at...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2011
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3190574/ https://ncbi.nlm.nih.gov/pubmed/21804022 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1101671 |
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