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Embryonic erythroid differentiation in the human leukemic cell line K562.

K562 human leukemia cells synthesize embryonic hemoglobins after culture in the presence of hemin. We have rigorously identified these hemoglobins by globin chain analysis and peptide mapping. No adult hemoglobin could be detected, and beta-globin synthesis was less than 2 ppm of total protein synth...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Rutherford, T, Clegg, J B, Higgs, D R, Jones, R W, Thompson, J, Weatherall, D J
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1981
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC319050/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6264439/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.1.348
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