Autocrine stimulation by erythropoietin and autonomous growth of human erythroid leukemic cells in vitro.

Autonomous colony formation is a frequent event in erythroleukemia. In 13 cases of early erythroid leukemias, we investigated whether erythropoietin (Epo) autocrine stimulation was responsible for the growth factor autonomy. Epo transcripts were detected by Northern blotting in cells from one patien...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Mitjavila, M T, Le Couedic, J P, Casadevall, N, Navarro, S, Villeval, J L, Dubart, A, Vainchenker, W
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1991
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295463/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1653276/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115378
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