Autocrine stimulation by erythropoietin and autonomous growth of human erythroid leukemic cells in vitro.

Autonomous colony formation is a frequent event in erythroleukemia. In 13 cases of early erythroid leukemias, we investigated whether erythropoietin (Epo) autocrine stimulation was responsible for the growth factor autonomy. Epo transcripts were detected by Northern blotting in cells from one patien...

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Pubblicato in:	J Clin Invest
Autori principali:	Mitjavila, M T, Le Couedic, J P, Casadevall, N, Navarro, S, Villeval, J L, Dubart, A, Vainchenker, W
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 1991
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295463/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1653276/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115378
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