Autocrine stimulation by erythropoietin and autonomous growth of human erythroid leukemic cells in vitro.

Autonomous colony formation is a frequent event in erythroleukemia. In 13 cases of early erythroid leukemias, we investigated whether erythropoietin (Epo) autocrine stimulation was responsible for the growth factor autonomy. Epo transcripts were detected by Northern blotting in cells from one patien...

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Publicado en:	J Clin Invest
Autores principales:	Mitjavila, M T, Le Couedic, J P, Casadevall, N, Navarro, S, Villeval, J L, Dubart, A, Vainchenker, W
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Clinical Investigation 1991
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295463/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1653276/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115378
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