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Autocrine stimulation by erythropoietin and autonomous growth of human erythroid leukemic cells in vitro.

Autonomous colony formation is a frequent event in erythroleukemia. In 13 cases of early erythroid leukemias, we investigated whether erythropoietin (Epo) autocrine stimulation was responsible for the growth factor autonomy. Epo transcripts were detected by Northern blotting in cells from one patien...

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Bibliografische gegevens
Gepubliceerd in:J Clin Invest
Hoofdauteurs: Mitjavila, M T, Le Couedic, J P, Casadevall, N, Navarro, S, Villeval, J L, Dubart, A, Vainchenker, W
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Clinical Investigation 1991
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295463/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1653276/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115378
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