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Embryonic erythroid differentiation in the human leukemic cell line K562.

K562 human leukemia cells synthesize embryonic hemoglobins after culture in the presence of hemin. We have rigorously identified these hemoglobins by globin chain analysis and peptide mapping. No adult hemoglobin could be detected, and beta-globin synthesis was less than 2 ppm of total protein synth...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Rutherford, T, Clegg, J B, Higgs, D R, Jones, R W, Thompson, J, Weatherall, D J
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1981
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC319050/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6264439/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.1.348
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