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Erythroid Differentiation Sensitizes K562 Leukemia Cells to TRAIL-Induced Apoptosis by Downregulation of c-FLIP

Regulation of the apoptotic threshold is of great importance in the homeostasis of both differentiating and fully developed organ systems. Triggering differentiation has been employed as a strategy to inhibit cell proliferation and accelerate apoptosis in malignant cells, in which the apoptotic thre...

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Detalhes bibliográficos
Main Authors: Hietakangas, Ville, Poukkula, Minna, Heiskanen, Kaisa M., Karvinen, Jarkko T., Sistonen, Lea, Eriksson, John E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC141136/
https://ncbi.nlm.nih.gov/pubmed/12556488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.4.1278-1291.2003
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