Erythroid Differentiation Sensitizes K562 Leukemia Cells to TRAIL-Induced Apoptosis by Downregulation of c-FLIP

Regulation of the apoptotic threshold is of great importance in the homeostasis of both differentiating and fully developed organ systems. Triggering differentiation has been employed as a strategy to inhibit cell proliferation and accelerate apoptosis in malignant cells, in which the apoptotic thre...

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Pubblicato in:	Mol Cell Biol
Autori principali:	Hietakangas, Ville, Poukkula, Minna, Heiskanen, Kaisa M., Karvinen, Jarkko T., Sistonen, Lea, Eriksson, John E.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Taylor & Francis 2003
Soggetti:	Cell Growth and Development
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC141136/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12556488/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.4.1278-1291.2003
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