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Erythroid Differentiation Sensitizes K562 Leukemia Cells to TRAIL-Induced Apoptosis by Downregulation of c-FLIP

Regulation of the apoptotic threshold is of great importance in the homeostasis of both differentiating and fully developed organ systems. Triggering differentiation has been employed as a strategy to inhibit cell proliferation and accelerate apoptosis in malignant cells, in which the apoptotic thre...

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Udgivet i:Mol Cell Biol
Principais autores: Hietakangas, Ville, Poukkula, Minna, Heiskanen, Kaisa M., Karvinen, Jarkko T., Sistonen, Lea, Eriksson, John E.
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2003
Fag:
Cell Growth and Development
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC141136/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12556488/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.23.4.1278-1291.2003
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