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Beta-globin gene promoter generates 5' truncated transcripts in the embryonic/fetal erythroid environment.

We report here the localisation of sequences responsible for the faulty expression of human beta-globin gene in Putko and K562 cells. Complete beta-globin gene introduced into these cells produces transcripts with abnormal 5' ends, while cotransfected mouse H2 gene is expressed correctly. Using...

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Bibliographische Detailangaben
Hauptverfasser: Khazaie, K, Gounari, F, Antoniou, M, deBoer, E, Grosveld, F
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1986
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC311746/
https://ncbi.nlm.nih.gov/pubmed/2429259
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