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Beta-globin gene promoter generates 5' truncated transcripts in the embryonic/fetal erythroid environment.
We report here the localisation of sequences responsible for the faulty expression of human beta-globin gene in Putko and K562 cells. Complete beta-globin gene introduced into these cells produces transcripts with abnormal 5' ends, while cotransfected mouse H2 gene is expressed correctly. Using...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
1986
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC311746/ https://ncbi.nlm.nih.gov/pubmed/2429259 |
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