Epigenetic Inactivation of GALR1 in Head and Neck Cancer

PURPOSE: One copy of the GALR1 locus on 18q is often deleted and expression is absent in some head and neck squamous cell carcinoma (HNSCC) cell lines. To determine if LOH and hypermethylation might silence the GALR1 gene, promoter methylation status and gene expression were assessed in a large pane...

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Библиографические подробности
Главные авторы: Misawa, Kiyoshi, Ueda, Yo, Kanazawa, Takeharu, Misawa, Yuki, Jang, Ilwhan, Brenner, John Chadwick, Ogawa, Tetsuya, Takebayashi, Satoru, Grenman, Reidar A., Herman, James G., Mineta, Hiroyuki, Carey, Thomas E.
Формат: Artigo
Язык:Inglês
Опубликовано: 2008
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3189853/
https://ncbi.nlm.nih.gov/pubmed/19047085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-07-4673
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