Aberrant Methylation Inactivates Somatostatin and Somatostatin Receptor Type 1 in Head and Neck Squamous Cell Carcinoma

PURPOSE: The aim of this study was to define somatostatin (SST) and somatostatin receptor type 1 (SSTR1) methylation profiles for head and neck squamous cell carcinoma (HNSCC) tumors at diagnosis and follow up and to evaluate their prognostic significance and value as a biomarker. METHODS: Gene expr...

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Veröffentlicht in:PLoS One
Hauptverfasser: Misawa, Kiyoshi, Misawa, Yuki, Kondo, Haruki, Mochizuki, Daiki, Imai, Atsushi, Fukushima, Hirofumi, Uehara, Takayuki, Kanazawa, Takeharu, Mineta, Hiroyuki
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4348545/
https://ncbi.nlm.nih.gov/pubmed/25734919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0118588
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