Galanin Has Tumor Suppressor Activity and Is Frequently Inactivated by Aberrant Promoter Methylation in Head and Neck Cancer

PURPOSE: There is accumulating evidence that galanin receptors (GALRs) may be tumor suppressors in head and neck squamous cell carcinoma (HNSCC). Promoter methylation status and gene expression were assessed in a large panel of primary tumors, based on the hypothesis that CpG hypermethylation might...

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Autori principali: Misawa, Kiyoshi, Kanazawa, Takeharu, Misawa, Yuki, Uehara, Takayuki, Imai, Atsushi, Takahashi, Goro, Takebayashi, Satoru, Cole, Andrew, Carey, Thomas E, Mineta, Hiroyuki
Natura: Artigo
Lingua:Inglês
Pubblicazione: Neoplasia Press Inc. 2013
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3660803/
https://ncbi.nlm.nih.gov/pubmed/23730414
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