Epigenetic Inactivation of GALR1 in Head and Neck Cancer

PURPOSE: One copy of the GALR1 locus on 18q is often deleted and expression is absent in some head and neck squamous cell carcinoma (HNSCC) cell lines. To determine if LOH and hypermethylation might silence the GALR1 gene, promoter methylation status and gene expression were assessed in a large pane...

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Detalhes bibliográficos
Main Authors: Misawa, Kiyoshi, Ueda, Yo, Kanazawa, Takeharu, Misawa, Yuki, Jang, Ilwhan, Brenner, John Chadwick, Ogawa, Tetsuya, Takebayashi, Satoru, Grenman, Reidar A., Herman, James G., Mineta, Hiroyuki, Carey, Thomas E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3189853/
https://ncbi.nlm.nih.gov/pubmed/19047085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-07-4673
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