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β-Cell Generation: Can Rodent Studies Be Translated to Humans?

β-cell replacement by allogeneic islet transplantation is a promising approach for patients with type 1 diabetes, but the shortage of organ donors requires new sources of β cells. Islet regeneration in vivo and generation of β-cells ex vivo followed by transplantation represent attractive therapeuti...

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Hlavní autoři: Carlotti, Françoise, Zaldumbide, Arnaud, Ellenbroek, Johanne H., Spijker, H. Siebe, Hoeben, Rob C., de Koning, Eelco J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3189575/
https://ncbi.nlm.nih.gov/pubmed/22007286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2011/892453
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