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Bioluminescent reporter assay for monitoring ER stress in human beta cells

During type 1 diabetes development, cells in the islets of Langerhans engage adaptive mechanisms in response to inflammatory signals to cope with stress, to restore cellular homeostasis, and to preserve cell function. Disruption of these mechanisms may induce the formation of a repertoire of stress-...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kracht, Maria J. L., de Koning, Eelco J. P., Hoeben, Rob C., Roep, Bart O., Zaldumbide, Arnaud
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6288136/
https://ncbi.nlm.nih.gov/pubmed/30532033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-36142-4
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