Controlled aggregation of primary human pancreatic islet cells leads to glucose-responsive pseudoislets comparable to native islets

Clinical islet transplantation is a promising treatment for patients with type 1 diabetes. However, pancreatic islets vary in size and shape affecting their survival and function after transplantation because of mass transport limitations. To reduce diffusion restrictions and improve islet cell surv...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Hilderink, Janneke, Spijker, Siebe, Carlotti, Françoise, Lange, Lydia, Engelse, Marten, van Blitterswijk, Clemens, de Koning, Eelco, Karperien, Marcel, van Apeldoorn, Aart
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2015
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4549034/
https://ncbi.nlm.nih.gov/pubmed/25782016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12555
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