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Reprogramming chaperone pathways to improve membrane protein expression in Escherichia coli

Because membrane proteins are difficult to express, our understanding of their structure and function is lagging. In Escherichia coli, α-helical membrane protein biogenesis usually involves binding of a nascent transmembrane segment (TMS) by the signal recognition particle (SRP), delivery of the SRP...

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Bibliographic Details
Main Authors: Nannenga, Brent L, Baneyx, François
Format: Artigo
Language:Inglês
Published: Wiley Subscription Services, Inc., A Wiley Company 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3189526/
https://ncbi.nlm.nih.gov/pubmed/21633988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.669
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