Investigations into the sequence-selective binding of mithramycin and related ligands to DNA.
The preferred binding sites for mithramycin on four different DNA fragments have been investigated by DNAase I footprinting. Sites containing at least two contiguous GC base pairs are protected by the antibiotic, the preferred binding site consisting of the dinucleotide step GpG (or CpC). Related an...
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| Опубликовано в:: | Nucleic Acids Res |
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| Главные авторы: | , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
1985
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| Online-ссылка: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC318945/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2934687/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/13.24.8695 |
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