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Protein interactions central to stabilizing the K(+) channel selectivity filter in a four-sited configuration for selective K(+) permeation
The structural and functional conversion of the nonselective NaK channel to a K(+) selective channel (NaK2K) allows us to identify two key residues, Tyr and Asp in the filter sequence of TVGYGD, that participate in interactions central to stabilizing the K(+) channel selectivity filter. By using pro...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3189067/ https://ncbi.nlm.nih.gov/pubmed/21933962 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1111688108 |
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