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Tuning the ion selectivity of tetrameric cation channels by changing the number of ion binding sites

Selective ion conduction across ion channel pores is central to cellular physiology. To understand the underlying principles of ion selectivity in tetrameric cation channels, we engineered a set of cation channel pores based on the nonselective NaK channel and determined their structures to high res...

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מידע ביבליוגרפי
Main Authors: Derebe, Mehabaw G., Sauer, David B., Zeng, Weizhong, Alam, Amer, Shi, Ning, Jiang, Youxing
פורמט: Artigo
שפה:Inglês
יצא לאור: National Academy of Sciences 2011
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3021048/
https://ncbi.nlm.nih.gov/pubmed/21187421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1013636108
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