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Tuning the ion selectivity of tetrameric cation channels by changing the number of ion binding sites
Selective ion conduction across ion channel pores is central to cellular physiology. To understand the underlying principles of ion selectivity in tetrameric cation channels, we engineered a set of cation channel pores based on the nonselective NaK channel and determined their structures to high res...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3021048/ https://ncbi.nlm.nih.gov/pubmed/21187421 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1013636108 |
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