Variants Near FOXE1 Are Associated with Hypothyroidism and Other Thyroid Conditions: Using Electronic Medical Records for Genome- and Phenome-wide Studies

We repurposed existing genotypes in DNA biobanks across the Electronic Medical Records and Genomics network to perform a genome-wide association study for primary hypothyroidism, the most common thyroid disease. Electronic selection algorithms incorporating billing codes, laboratory values, text que...

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主要な著者: Denny, Joshua C., Crawford, Dana C., Ritchie, Marylyn D., Bielinski, Suzette J., Basford, Melissa A., Bradford, Yuki, Chai, High Seng, Bastarache, Lisa, Zuvich, Rebecca, Peissig, Peggy, Carrell, David, Ramirez, Andrea H., Pathak, Jyotishman, Wilke, Russell A., Rasmussen, Luke, Wang, Xiaoming, Pacheco, Jennifer A., Kho, Abel N., Hayes, M. Geoffrey, Weston, Noah, Matsumoto, Martha, Kopp, Peter A., Newton, Katherine M., Jarvik, Gail P., Li, Rongling, Manolio, Teri A., Kullo, Iftikhar J., Chute, Christopher G., Chisholm, Rex L., Larson, Eric B., McCarty, Catherine A., Masys, Daniel R., Roden, Dan M., de Andrade, Mariza
フォーマット: Artigo
言語:Inglês
出版事項: Elsevier 2011
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Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3188836/
https://ncbi.nlm.nih.gov/pubmed/21981779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2011.09.008
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