Variants Near FOXE1 Are Associated with Hypothyroidism and Other Thyroid Conditions: Using Electronic Medical Records for Genome- and Phenome-wide Studies

We repurposed existing genotypes in DNA biobanks across the Electronic Medical Records and Genomics network to perform a genome-wide association study for primary hypothyroidism, the most common thyroid disease. Electronic selection algorithms incorporating billing codes, laboratory values, text que...

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Detaylı Bibliyografya
Asıl Yazarlar: Denny, Joshua C., Crawford, Dana C., Ritchie, Marylyn D., Bielinski, Suzette J., Basford, Melissa A., Bradford, Yuki, Chai, High Seng, Bastarache, Lisa, Zuvich, Rebecca, Peissig, Peggy, Carrell, David, Ramirez, Andrea H., Pathak, Jyotishman, Wilke, Russell A., Rasmussen, Luke, Wang, Xiaoming, Pacheco, Jennifer A., Kho, Abel N., Hayes, M. Geoffrey, Weston, Noah, Matsumoto, Martha, Kopp, Peter A., Newton, Katherine M., Jarvik, Gail P., Li, Rongling, Manolio, Teri A., Kullo, Iftikhar J., Chute, Christopher G., Chisholm, Rex L., Larson, Eric B., McCarty, Catherine A., Masys, Daniel R., Roden, Dan M., de Andrade, Mariza
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Elsevier 2011
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3188836/
https://ncbi.nlm.nih.gov/pubmed/21981779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2011.09.008
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