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Selection of initiation sites by eucaryotic ribosomes: effect of inserting AUG triplets upstream from the coding sequence for preproinsulin.

Recombinant plasmids that direct synthesis of rat preproinsulin under the direction of the SV40 early promoter have been used to probe the mechanism of initiation of translation. Insertion of an upstream AUG triplet that was out-of-frame with respect to the coding sequence for preproinsulin reduced...

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Hlavní autor: Kozak, M
Médium: Artigo
Jazyk:Inglês
Vydáno: 1984
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC318796/
https://ncbi.nlm.nih.gov/pubmed/6328442
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