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Possible role of flanking nucleotides in recognition of the AUG initiator codon by eukaryotic ribosomes.
Sequences flanking the initiator codon in eukaryotic mRNAs are not random. Out of 153 messages examined, 151 have either a purine in position -3, or a G in position +4, or both. Thus, [A/G]XXAUGG emerges as the favored sequence for eukaryotic initiation sites. Nucleotides flanking nonfunctional AUG...
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| Formato: | Artigo |
| Idioma: | Inglês |
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1981
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC327517/ https://ncbi.nlm.nih.gov/pubmed/7301588 |
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