Influences of mRNA secondary structure on initiation by eukaryotic ribosomes.
Oligonucleotides designed to create hairpin structures were inserted upstream from the ATG initiator codon in several plasmids that encode preproinsulin, and the effects on translation were monitored in COS cells transfected by the vectors. Creation of a hairpin (delta G = -30 kcal/mol) that directl...
保存先:
| 出版年: | Proc Natl Acad Sci U S A |
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| 第一著者: | |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
1986
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC323404/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3458245/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.9.2850 |
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