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Influences of mRNA secondary structure on initiation by eukaryotic ribosomes.

Oligonucleotides designed to create hairpin structures were inserted upstream from the ATG initiator codon in several plasmids that encode preproinsulin, and the effects on translation were monitored in COS cells transfected by the vectors. Creation of a hairpin (delta G = -30 kcal/mol) that directl...

詳細記述

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書誌詳細
第一著者: Kozak, M
フォーマット: Artigo
言語:Inglês
出版事項: 1986
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC323404/
https://ncbi.nlm.nih.gov/pubmed/3458245
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