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Selection of initiation sites by eucaryotic ribosomes: effect of inserting AUG triplets upstream from the coding sequence for preproinsulin.

Recombinant plasmids that direct synthesis of rat preproinsulin under the direction of the SV40 early promoter have been used to probe the mechanism of initiation of translation. Insertion of an upstream AUG triplet that was out-of-frame with respect to the coding sequence for preproinsulin reduced...

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Bibliografische gegevens
Gepubliceerd in:Nucleic Acids Res
Hoofdauteur: Kozak, M
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 1984
Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC318796/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6328442/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/12.9.3873
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